Radiohalogenation method

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...

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Details

2602395, 424 9, 424238, A61K 4300, A61K 4900

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active

044501498

ABSTRACT:
Organoborane compounds are halogenated by reacting an organoborane with iodinemonochloride, brominemono-chloride or a halide salt in the presence of a mild oxidizing agent.

REFERENCES:
patent: 4184037 (1980-01-01), Wilkinson
Kabalka et al., J. Nucl. Med., 22:208-912, 1981.
De Lue et al., Synthesis, 2:114-116, 1976.
Kabalka et al., Chemical Abstracts, 96 (1982) Abstract #51928y.
Kabalka et al., Chemical Abstracts, 93 (1980) Abstract #132002g.
Kabalka et al., Chemical Abstracts, 95 (1981) Abstract #6665d.
Kabalka et al., Chemical Abstracts, 95 (1981) Abstract #203260u.
Gooch et al., Diss. Abstracts B, 42:1892, 1981.
Collins et al., J. Medicinal Chem., 20:1152-1159, 1977.

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