Radiohalogenated half-antibodies and maleimide intermediate ther

Details Radiohalogenated half-antibodies and maleimide intermediate ther Radiohalogenated half-antibodies and maleimide intermediate ther

1988-01-29

1991-02-19

Springer, David B.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

548549, C07D20727, A61K 3700

Patent

active

049945572

ABSTRACT:
N-(m-radiohalophenyl) maleimide can be conjugated with a reduced antibody having a mercapto group to provide a radiolabelled half-antibody having immunological specific binding characteristics of whole antibody.

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patent: 4735792 (1988-04-01), Srivestava
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