Radiographic scanning agent

Details Radiographic scanning agent Radiographic scanning agent

1978-07-31

1981-01-27

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

424 15, 424 9, 128654, A61K 4900, A61K 4300, G01T 100

Patent

active

042475341

ABSTRACT:
A composition and method for the preparation of a technetium-99m-based scanning agent are disclosed. The scanning agent is prepared from .sup.99m Tc, in a +3, +4 and/or +5 oxidation state, and a methanehydroxydiphosphonate bone-seeking agent which carries the radionuclide to bone mineral. The methanehydroxydiphosphonate agent provides scan sharpness equivalent or superior to commercial scanning agents, and is superior for detecting myocardial infarcts, as compared with commercial scanning agents such as ethane-1-hydroxy-1,1-diphosphonate and methanediphosphonate.

REFERENCES:
patent: 3983227 (1976-09-01), Tofe et al.

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