Radiofrequency plasma biocompatibility treatment of inside surfa

Details Radiofrequency plasma biocompatibility treatment of inside surfa Radiofrequency plasma biocompatibility treatment of inside surfa

1991-06-25

1993-09-14

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

424422, 424423, 427 2, 427238, 427569, 525 541, 525 542, 525406, 525423, 525424, 525430, 525449, 525453, 525454, 525474, 525937, 604 96, 604239, 21050024, 264 14, 522915, 523112, 530816, A61L 3300, A61L 2900, A61K 3562, A61K 31725, B05D 306

Patent

active

052446549

ABSTRACT:
Internal polymeric surfaces of medical devices are provided that have enhanced biocompatibility properties. The internal polymeric surface presents an anti-thrombogenic, fibrinolytic or thrombolytic interface with body fluids such as blood flowing through medical device tubing during implantation for medical procedures. The biocompatibility enhancing agent is secured to the polymeric substrate by a spacer molecule which is covalently bound to the internal polymeric surface which had been subjected to radiofrequency plasma treatment with a low pressure plasma medium of water vapor, oxygen or combination of water vapor and oxygen gas.

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