Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase
Patent
1981-09-02
1983-12-27
Kepplinger, Esther M.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving transferase
435184, 435193, 436804, C12Q 148, C12N 910, C12N 999
Patent
active
044231440
ABSTRACT:
A new radioenzymatic assay for catecholamines utilizing the catechol-O-methyl transferase transfer of a methyl group from a labeled methyl donor to the catecholamines followed by isolation of the O-methylated(H)catecholamine and the subsequent measurement of radioactivity.
REFERENCES:
patent: 4284587 (1981-08-01), Johnson et al.
patent: 4288542 (1981-09-01), Johnson et al.
Weinshilboum et al., "Calcium Inhibition of Rat Liver Catechol-O-Methyltransferase," Biochemical Pharmacology, vol. 25, (1976), pp. 573-579.
Engelman et al., "A Sensitive and Specific Double-Isotope Derivative Method for the Determination of Catecholamines in Biological Specimens", The Amer. J. of the Med. Sci., vol. 255, (Apr. 1968), pp. 259-268.
Cuello et al., "Use of Cutechot-O-Methyltransferase for the Enzyme Radrochemical Assay of Dopamine", J. Neurochemistry, vol. 21, (1973), pp. 1337-1340.
Axelrod et al., "Enzymatic O-Methylation of Epinephrine and Other Catechols", J. Biol. Chem., vol. 233, No. 3, (1958), pp. 702-705.
Champlain et al., "Circulating Catecholamine Levels in Human and Experimental Hypertension", Circulation Res., vol. 38, No. 2, (Feb. 1976), pp. 109-112.
Yamaguchi et al., "Correlation Between the Response of the Heart to Sympathetic Stimulation and the Release of Endogenous Catecholamines into the Coronary Sinus of the Dog", Circulation Res., vol. 36, (May 1975), pp. 662-668.
Engleman et al., "A Sensitive Double Isotope Derivative Assay for Norepinephrine and Epinephrine", Circulation Res., vol. 26, (Jan. 1970), pp. 53-57.
Christensen, "A Sensitive Assay for the Determination of Dopamine in Phasma", Scand. J. Clin. Lab. Invest., vol. 31, (1973), pp. 343-346.
Passon et al., "A Simplified Radiometric Assay For Plasma Norepinephrine and Epinephrine", Anal. Biochem., vol. 51, No. 2, (Feb. 1973), pp. 618-631.
Coyle et al., "Catecholamines in Fetal and Newborn Rat Brains", J. Neurochemistry, vol. 21, (1973), pp. 61-67.
Raymond et al., "Microassay of Human Erythrocyte Catechol-O-Methyltransferrase, Removal of Inhibitory Calcium Ion With Chelating Resin", Clinica Chim. Acta., vol. 58, (1975), pp. 185-194.
Johnson Garland A.
Peuler Jacob D.
Hattan L. Ruth
Kepplinger Esther M.
The Upjohn Company
LandOfFree
Radioenzymatic assay of catecholamines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Radioenzymatic assay of catecholamines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Radioenzymatic assay of catecholamines will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-947870