Radioenzymatic assay of catecholamines

Details Radioenzymatic assay of catecholamines Radioenzymatic assay of catecholamines

1978-10-12

1981-08-18

Gron, Teddy S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

23230B, 210635, 210639, 210658, 252408, 568442, 424 1, 424 15, 424 2, 424330, 435 4, 435 15, 435193, 564374, G01N 3100, G01N 3108, G01N 3348, B01D 904, B01D 1104, B01D 1508, C07C 9130, C07C 9134

Patent

active

042845874

ABSTRACT:
A new radioenzymatic assay for catecholamines utilizing the catechol-O-methyl transferase transfer of a methyl group from a labeled methyl donor to the catecholamines followed by isolation of the O-methylated(.sup.3 H)catecholamine and the subsequent measurement of radioactivity.

REFERENCES:
patent: 3254989 (1966-06-01), Olds
patent: 3289838 (1966-12-01), Garrett
patent: 3993555 (1976-11-01), Park et al.
Passon, P. G., et al, Anal. Biochem., vol. 51, pp. 618-631 (1973).
Coyle, J. T., et al., J. Neuro Chem., vol. 21, pp. 61-67 (1973).
Vogel, A. I., "Practical Organic Chemistry", Longmans, Green & Co., N. Y., pp. 156-161, 944-946, (1948).

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