Radiodiagnostic complexes employing fluorine-containing tin redu

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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260429R, 424 9, A61K 2900, A61K 4300

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active

040546454

ABSTRACT:
Radiodiagnostic agents for use in mammalian bodies comprising a radiocomplex which is the reaction product of Tc99m-pertechnetate ion, a diagnostic ligand and a tin (II) reducing agent selected from the group consisting of SnF.sub.2, MSnF.sub.3, MSn.sub.2 F.sub.5 and mixtures thereof, wherein M is NH.sub.4, Na, K, Li, Rb or Cs. Radiocomplex precursor compositions and methods of making the radiocomplex and radiodiagnostic agents are described.

REFERENCES:
patent: 3466361 (1969-12-01), Richards et al.
patent: 3749556 (1973-07-01), Barak et al.
patent: 3873680 (1975-03-01), Jackson et al.
patent: 3987157 (1976-10-01), Molinski et al.
Chervu et al., Radiology, vol. 107, May, 1973, pp. 435-437.
Gil et al., International Journal of Applied Radiation and Isotopes, vol. 27, No. 2, Feb., 1976, pp. 69-72.

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