Radioactive stilbene derivatives in radioimmunoassay

Details Radioactive stilbene derivatives in radioimmunoassay Radioactive stilbene derivatives in radioimmunoassay

1982-06-22

1985-07-16

Schwartz, Richard A.

Chemistry: analytical and immunological testing

Involving producing or treating antigen or hapten

Producing labeled antigens

436804, 548337, 560 40, 560 61, 562444, 562471, 564174, G01N 3356

Patent

active

045297134

ABSTRACT:
Novel radioactive stilbene derivatives marked with iodine 125 or 131 of the formula ##STR1## wherein each A and B are both hydrogen or together form a double bond and R is the remainder of amino acid of the formula R--NH.sub.2 or a derivative thereof possessing an iodine acceptor group and marked with iodine 125 or 131 and their preparation and antigens obtained therefrom and a process for preparing said antigens.

REFERENCES:
patent: 4310675 (1982-01-01), Akerkar et al.
Gutierrez-Cernosek, R., et al., Ann. Clin. Lab. Sci. 7(1), 35(1977).
Fruton, J., et al., General Biochemistry, John Wiley, New York, 1953, p. 672.
Raith, L., Introduction to Radioimmunoassay Methods, Kirn and Birner, Frankfurt, 1975, pp. 3-31.
Chemical Abstracts, Chemical Subject Index to 9th Collective Edition, p. 27736cs, (1976).
Chemical Abstracts, 92:41489j, (1980) [Johnson, et al., J. Labelled Compd. Radiopharm., 1979, 16(3), 501-6].
Hunter, W., in Handbook of Exp. Immunology, 2nd ed., 1973, pp. 17.1-17.35.

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