Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Patent
1994-10-05
1998-03-17
Achutamurthy, Ponnathapura
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
424153, 424173, 424177, 4241791, 5303913, 5303915, 530404, 530405, 530408, 530409, C07K 113, A61K 3944, A61K 5110
Patent
active
057283699
ABSTRACT:
.sup.32 P- and .sup.33 P-labeled proteins which are useful for radiotherapy are prepared by stably linking .sup.32 P- or .sup.33 P- containing molecules to targeting proteins in such a way that the targeting protein retains the ability to bind to a cellular target. Methods for preparing the labeled proteins and their use in methods of radiotherapy are described.
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Craeighton et al. "The development of .sup.32 P technology for radioimmunotherapy" in Monoclonal Antibodies 2. Applications in Clinical Oncology, A.A. Epenetos, ed., Chapman and Hall, (1993) pp. 103-109.
Griffiths Gary L.
Hansen Hans J.
Karacay Habibe
Achutamurthy Ponnathapura
Immunomedics Inc.
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