Radioactive iodine-labeled compound

Details Radioactive iodine-labeled compound Radioactive iodine-labeled compound

2005-07-12

2005-07-12

Morris, Patricia L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

06916930

ABSTRACT:
A radioactive iodine-labeled compound represented by the following formulawherein X represents a radioactive iodine atom which may substitute at an arbitrary position on the benzene ring (preferably123I,125I and the like.), n represents an integer of 1 to 3, R1and R2each independently represent a substituted or unsubstituted alkyl group, Y represents an alkylene group having 1 to 6 carbon atoms (preferably methylene group), M represents a counter ion, and m represents the number of ions required to neutralize the charge of the molecule. A radioactive iodine-labeled compound that can selectively accumulate in tumor cells or tumor tissue and a scintillation imaging agent containing the compound are provided.

REFERENCES:
Kawakami et al., “Synthesis and Evaluation of Novel Rhodacyanine, etc., ” J. Med. Chem. 1997, 40, 3151-3160.

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