Radioactive diagnostic agent for bone scanning and non-radioacti

Details Radioactive diagnostic agent for bone scanning and non-radioacti Radioactive diagnostic agent for bone scanning and non-radioacti

1981-09-11

1984-03-27

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, A61K 4300, A61K 4900

Patent

active

044394136

ABSTRACT:
A radioactive diagnostic agent for bone scanning, which comprises .sup.99m Tc and a non-radioactive carrier comprising (A) at least one chosen from methanehydroxydiphosphonic acid and their salts and (B) at least one reducing agent for pertechnetates in a weight ratio of about 1:1 to 7:1 and prevents the accumulation of radioactivity in liver so that definite diagnosis can be assured.

REFERENCES:
patent: 4229427 (1980-10-01), Whitehouse
patent: 4232000 (1980-11-01), Fawzi
patent: 4233284 (1980-11-01), Fawzi
patent: 4234562 (1980-11-01), Tofe et al.
patent: 4247534 (1981-01-01), Bevan
Barnes et al., Int. J. Appl. Rad. Isotopes, 32(3), 174-175 (1981).
Domstad et al., Radiology, 136(1), 209-211 (1980).

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