Radioactive and non-radioactive iodobutyrophenone derivative

Details Radioactive and non-radioactive iodobutyrophenone derivative Radioactive and non-radioactive iodobutyrophenone derivative

1986-08-14

1988-04-19

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D47110

Patent

active

047390603

ABSTRACT:
A radioactive or non-radioactive 2-iodobutyrophenone derivative the formula: ##STR1## wherein X is a radioactive or non-radioactive iodine atom. The radioactive compound has a high affinity for dopamine receptors and is very useful as a radioactive diagnostic agent and as a radiopharmaceutical, and the non-radioactive compound also as a high affinity for dopamine receptors and is very useful as a neuroleptic, a sedative, an anodyne, a tranquilizer, etc.

REFERENCES:
patent: 3155669 (1964-11-01), Janssen
patent: 3890323 (1975-06-01), Yamamoto et al.
patent: 3979390 (1976-09-01), Sasajima et al.
Glowinski et al., "J of Neurochemistry" (1966), vol. 13, pp. 655-669.

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