Radio labeled dihematophorphyrin ether and its use in detecting

Details Radio labeled dihematophorphyrin ether and its use in detecting Radio labeled dihematophorphyrin ether and its use in detecting

1985-02-06

1992-04-14

Stoll, Robert L.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 9, 540145, A61K 4902, A61K 4300

Patent

active

051046377

ABSTRACT:
Radiolabeled dihematoporphyrin ether having the following general formula ##STR1## wherein at least one of R.sub.1 -R.sub.6 is a moiety labeled with a radionuclide imaging agent is useful in providing a non-invasive nuclear scintillation image. This dihematoporphyrin ether localizes in neoplastic tissue and thus provides a method of imaging and recording the location of neoplastic tissue. When the labeling agent has an adequate component of particulate radiation, the dihematoporphyrin ether can be used as a therapeutic agent as well as a diagnostic imaging agent.

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