Radio frequency plasma deposited polymers that enhance cell grow

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure

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623 66, 429 2, 429 40, 429 41, 435240, 435243, 435285, A61F 206

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049196596

ABSTRACT:
A method for enhancing bio-material capability for use as a supporting surface for cell culture is disclosed. The method requires exposure of the bio-material to a plasma polymerizable polymer gas, which includes oxygen-containing organic molecules. The material surfaces are then subjected to an RF plasma gas discharge in the presence of the gas, causing a deposition on the exposed material surfaces of a conformal overcoating of the polymer on the material. The deposition enhances fibronectin adsorption and hence cell attachment, spreading and cell growth. Preferred polymerizable gases are acetone, methanol, and ethylene oxide.

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