Radio frequency-induced hyperthermia for tumor therapy

Details Radio frequency-induced hyperthermia for tumor therapy Radio frequency-induced hyperthermia for tumor therapy

1983-11-21

1986-03-11

Rosenberg, Peter D.

Surgery

Truss

Perineal

A61B 1752

Patent

active

045747822

ABSTRACT:
This invention is directed to a method for reducing the mass of a tumor in animal tissue utilizing localized, magnetically-coupled, RF-induced hyperthermia. The method involves the implanting of a material in and/or closely adjacent to the tumor which is non-toxic to, and preferably inert to and compatible with, normal tissue and which has encapsulated therewithin ferromagnetic particles of such size, amount, composition, and ferromagnetism to develop a heating value of up to about one watt/gram, through essentially only hysteresis heating, under an applied field of about 20 but less than 200 oersteds at a frequency greater than 10 kilohertz and ranging up to about 600 kilohertz, or under an applied field of at least about 2000 oersteds and a frequency below about 40 hertz. Such heating value is sufficient to kill the tumor cells but muscle and nerve response of the animal body to the induced emf is minimized.

REFERENCES:
patent: 4323056 (1982-04-01), Borrelli
patent: 4369345 (1983-01-01), Czerlinski

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