Radio-assay of oestrogen

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23230B, 1951035A, G01N 3114, G01N 3316

Patent

active

040627330

ABSTRACT:
A method for the radio-assay of an oestrogen in a biological fluid which method comprises causing the oestrogen to compete with a radio-iodine derivative, selected from the group consisting of the 2-iodo-, 4-iodo- and 2,4-di-iodo- derivatives of the oestrogen, for reaction with a specific reagent for the oestrogen, separating the oestrogen and iodo-oestrogen bound to the specific reagent from the unbound oestrogen and iodo-oestrogen and measuring the radioactive concentration of one or both the bound and unbound fractions of oestrogen.

REFERENCES:
patent: 3654090 (1972-04-01), Schuurs et al.
patent: 3896217 (1975-07-01), Johnson
Hawker, Analytical Chemistry, vol. 45, No. 11, pp.878-888 (1973).

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