Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Aftertreated polymer
Patent
1993-12-06
1997-03-11
Kulkosky, Peter F.
Drug, bio-affecting and body treating compositions
Solid synthetic organic polymer as designated organic active...
Aftertreated polymer
422 22, 422 37, 424667, 424668, A61K 3179, A61K 200
Patent
active
056098669
ABSTRACT:
Sterilized povidone-iodine (polyvinylpyrrolidone-iodine) in an ointment form is obtained by preparation of a mixture of purified water, povidone-iodine, a non-ionic gelling agent, and a non-ionic low suds surfactant. The ointment is a liquid in the temperature range of about 2.degree. C. to 9.degree. C. because of the influence of the non-ionic gelling agent. At room temperature, the mixture forms a free standing ointment which can be sterilized by gamma radiation without degradation of its antimicrobial efficacy, viscosity or shelf life. The ointment is easily prepared by using chilled purified water which maintains the mixture as a liquid while all of the ingredients are mixed together. At room temperature the mixture becomes a free standing ointment.
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Khan Mohammed A.
Moellmer John F.
Becton Dickinson and Company
Kulkosky Peter F.
Thomas Nanette S.
Weintraub Bruce S.
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