Radiating device for hyperthermia

Surgery – Instruments – Heat application

Reissue Patent

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Details

C607S102000, C607S105000, C606S042000

Reissue Patent

active

RE037315

ABSTRACT:

BACKGROUND OF THE INVENTION
This invention concerns a radiating device for hyperthermia and, more particularly, a radiofrequency radiating device, for hyperthermal treatment of tumors of the bladder.
Devices for hyperthermal treatment of various human body illnesses are already known, and they use heating liquids, light radiations, radiofrequency antennas, thermistors, and so on.
U.S. Pat. No. 4,776,334 describes a catheter for treating tumors by inserting within the tumor to be treated a radiofrequency device provided with temperature sensors.
French patent application 2600205 concerns an apparatus for light irradiation of a cavity with the help of an inflatable balloon and of light sensors.
In U.S. Pat. No. 4,154,246 there is described a radiofrequency resonating circuit which is introduced in natural cavities of the body or directly inserted into the tumoral mass.
German patent application No. 2,848,636 claims usage of a heated liquid which is circulated in a closed loop by means of a pump within a body cavity, wherein the liquid temperature is controlled by an external thermostat. EP-A-0 370 890 discloses a radiating urethral device for hyperthermia including a catheter provided with an inflatable balloon and adapted to receive one or more liquid flows passing therethrough, a radiofrequency radiating antenna, and one or more thermocouples, the radiating antenna being submerged within one said liquid flow coming back from the closed terminal end of the antenna. The radiating device comprises in addition a separate rectal control means.
GB-A-2 045 620 relates to an applicator for hyperthermia comprising a rectal radiating probe and a spaced apart transurethral catheter including a temperature sensing means and an inflatable balloon. U.S. Pat. No. 4,957,765 discloses a transurethral radiating applicator for hyperthermia including a multi-tubes balloon type catheter comprising closed end tubes respectively surrounding a helical coil antenna and a temperature sensor, as well as a passive drainage tube for urine.
It is an object of this invention to provide a device for hyperthermal treatment of tumors within natural cavities of the human body, which gathers the advantages of the known devices while being free from their drawbacks.
SUMMARY OF THE INVENTION
The device according to this invention substantially comprises a flexible triple path catheter carrying a radiofrequency radiating antenna, sealingly sheathed together with the shielded cable providing power supply and with several thermocouples within a plastic casing and surrounded by a flow of liquid; a second path carries the power supply cables for several outer thermocouples, which are flooded by return flow of said liquid, and a third path allowing a fluid to flow through in order to inflate a balloon located near the catheter distal end, once the latter has been introduced into the cavity to be treated.
This invention will be described more particularly in the following based on a specific embodiment thereof reported herein for exemplary and non limiting purposes, as well as on the attached schematic drawings. In connection with the above it should be pointed out that in said drawings the parts shown are not to scale and the mutual dimensions are out of proportion, the members having in fact a very thin cross-section.


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Z. Leib et al., “Mitomycin C (MMC) vs. MMC Combined with Local Microwave Hyperthermia (LMWH) as Prophylaxis of Recurrence of Superficial Transitional Bladder Cancer: A Preliminary Report,” Poster presented at The XIIth Congress of The European Association of Urology, Paris, Sep. 1-4, 1996.
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R. Colombo et al., “Neoadjuvant Combined Microwave Induced Local Hyperthermia and Topical Chemotherapy Versus Chemotherapy Alone for Superficial Bladder Cancer,” J. Urology, vol. 155, No. 4, pp. 1227-1232, (Apr. 1996).
R. Colombo et al., “A New Approach Using Local Combined Microwave Hyperthermia and Chemotherapy in Superficial Transitional Bladder Carcinoma Treatment,” J. Urology, vol. 153, pp. 959-963, (Mar. 1995).

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