Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1995-02-10
1997-09-16
Chin, Christopher L.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
436169, 436528, 436538, 436524, 436807, 436809, 435 791, 4352871, 4352877, 4352879, 435810, 435970, 422 56, 422 57, 422 58, 422 60, 422 681, 422 99, 422101, G01N 2100, G01N 3122, G01N 3353, G01N 33543
Patent
active
056680171
ABSTRACT:
The assay device of this invention provides for very simple assay procedures leading to rapid, sensitive, specific detection of an analyte in a solution. The device is inexpensive and easily manufactured, particularly if automated manufacturing processes are used. The assay device is a test strip having an elongated support sheet of solid non-porous material attached to a similarly shaped sheet of absorbent material. The absorbent sheet has perforations, preferably of circular shape, forming sample receiving wells. Forming the bottom of the sample receiving wells is one surface of the support sheet, and attached to this surface are moieties which specifically bind the analyte (anti-analyte moieties). A liquid sample for assay is placed in the wells, and the liquid is drawn into the absorbent material. As the liquid is absorbed, it flows tangentially across the surface of the support sheet, and across binding moieties specific for the analyte which are attached to the bottom of the wells. If analyte is present in the sample, analyte will form a complex with anti-analyte attached to the support surface, and detection of the complex will demonstrate the presence of the analyte.
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Buchanan Ian Ellis
Tam Milton Richard
Chin Christopher L.
Nguyen Bao-Thuy L.
Path
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