Racemization of optically active 2-(4-chlorophenyl)-3-methylbuty

Details Racemization of optically active 2-(4-chlorophenyl)-3-methylbuty Racemization of optically active 2-(4-chlorophenyl)-3-methylbuty

1978-12-11

1981-01-13

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562496, C07B 2000

Patent

active

042451167

ABSTRACT:
A method for racemization of optically active 2-(4-chlorophenyl)-3-methylbutyric acid which comprises the steps of (a) reacting optically active 2-(4-chlorophenyl)-3-methylbutyric acid with a hydroxide or carbonate of an alkali metal or alkaline earth metal at a temperature of more than 110.degree. C. to produce a racemate of the alkali metal or alkaline earth metal salt of the above acid, and (b) converting the resulting racemate of the salt to the acid.

REFERENCES:
patent: 2859244 (1958-11-01), White
patent: 3213106 (1965-10-01), Sasaji et al.
patent: 3686183 (1972-08-01), Dyson

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