Racemization of amino acids

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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525377, 525384, 548498, 549332, 560 39, 560 40, 560155, 560169, 560170, 560171, 562401, 564162, 564166, 564171, 564193, 564194, 564197, 564198, 564201, 564202, C07B 5700

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047134704

ABSTRACT:
There is disclosed a process for the racemization of amino acids and derivatives thereof. The racemization process of the present invention uses an aromatic aldehyde-containing polymer made from the reaction of a hydroxy-aromatic aldehyde with a chloromethylated vinylbenzene polymer under reaction conditions to form an aromatic aldehyde-containing polymer wherein the aldehydic moiety is linked to the polymer through an ether linkage. There is also disclosed a process for the production of the racemization catalyst. Another embodiment of the invention comprises a process for the promotion of the racemization reaction wherein a tertiary amine-containing resin is used as a promoting agent.

REFERENCES:
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Pugniere et al., Biotechnology Letters, 1, 31-36, (1985).
Toi et al., Bull. Chem. Soc., Jpn, 35, 1422-1423, (1962).
Toi et al., Bull. Chem. Soc., Jpn., 36, 734-737, (1963).
Toi et al., Bull. Chem. Soc., Jpn., 36, 739-742, (1963).
Abstract of Japanese 13445/67, 7-28-67.
Yamaskov et al., Polymer Sci., 21, 2031-2037, (1980).

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