Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2007-08-09
2008-08-05
Barts, Samuel A (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
Reexamination Certificate
active
07408082
ABSTRACT:
The present invention relates to a novel process for obtaining (1S,4S)N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthaleneamine from a mixture of its isomers. The process involves isomerising the 1-position and the 4-position and effecting separation of the desired isomer by methods such as fractured crystallization. The process can be operated as a continuous process.
REFERENCES:
patent: WO-92/15552 (1992-09-01), None
patent: WO-2005/023752 (2005-03-01), None
Barts Samuel A
Foley & Hoag LLP
Gordon Dana M.
NPIL Pharmaceuticals (UK) Limited
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