Racemic conversion of using a transaminase

Chemistry: molecular biology and microbiology – Process of utilizing an enzyme or micro-organism to destroy... – Resolution of optical isomers or purification of organic...

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Details

435106, 435108, 435110, 435116, 435115, C12P 1304

Patent

active

053169433

ABSTRACT:
Recombinant cells and an improved method utilizing them is disclosed for the preparation of an optically pure, L-amino acid from its D and D,L isomer forms. The process utilizes cell cultures that possess high aminotransferase activity that exhibits moderate selectivity in the conversion of D and L amino acids to their respective 2-keto acids as well as absolute stereospecificity in the conversion of the 2-keto acids to the L isomer alone.

REFERENCES:
patent: 4518692 (1985-05-01), Rozzell
patent: 4745061 (1988-05-01), Aretz et al.

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