Rabbit immunoglobulin-N-(3-pyrene)-maleimide conjugate for fluor

Details Rabbit immunoglobulin-N-(3-pyrene)-maleimide conjugate for fluor Rabbit immunoglobulin-N-(3-pyrene)-maleimide conjugate for fluor

1978-08-08

1980-06-10

Marantz, Sidney

Chemistry: physical processes

Physical processes

Crystallization

252408, 260112R, 424 8, 424 12, G01N 3316, G01N 2100

Patent

active

042070759

ABSTRACT:
A fluorometric technique which uses a detecting fluorophore for determining the quantitative levels of human immunoglobulin. The detecting fluorophore is an N-(3-pyrene)-maleimide conjugated immunoglobulin which shows enhanced quantum yield in the presence of human immunoglobulin molecules. Measuring the resulting changes in fluorescent emission determines the concentration level of the human immunoglobulin present in a test sample since the induced changes in fluorescence are directly proportional to the protein concentration.

REFERENCES:
patent: 3720760 (1973-03-01), Bennich
patent: 3817706 (1974-06-01), Smith
patent: 3904373 (1975-09-01), Harper
patent: 3960840 (1976-06-01), Secrist
patent: 4018884 (1977-04-01), Cleeland, Jr.
patent: 4036946 (1977-07-01), Kleinerman
Robert P. Liburdy, J. Immuno. Methods, 28, 243-253 (1979).
R. P. Liburdy et al., Abstract Federation Proceedings, 36:1089 (1977).
R. P. Liburdy et al., Cell Motility, vol. 3, pp. 229-234 (1976).
R. P. Liburdy et al., Abstract, 166th National Meeting Am. Chem. Soc., Chic., Ill., Biol #097, 1973.
J. K. Weltman et al., J. Biol. Chem., 248(9), 3173-3177 (1973).
J. J. Munoz, Anal. Chem., 31 (6), 981-985 (1959).
Chemical Abstracts, 85:59091p (1976).
R. P. Liburdy, Ph. D. Thesis, Brown Univ., Providence, Rhode Island, 1975.

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