R(+)-terazosin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544291, A61K 31505, C07D23984

Patent

active

052121763

ABSTRACT:
R(+)-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-6,7-dimethoxy-4-q uinazolinamine hydrochloride or a pharmaceutically acceptable salt or hydratet hereof (terazosin), substantially free of the S(-)-enantiomer.

REFERENCES:
patent: 4026894 (1977-05-01), Winn et al.
patent: 4112097 (1978-09-01), Winn et al.
patent: 4251532 (1981-02-01), Roteman
"Advanced Organic Chemistry" by Jerry March (1985) John Wiley & Sons publishers pp. 82-87.
T. Nagatomo, et al., Chem. Pharm. Bull. 35(4)1629-1632 (1987).

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