Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-06-29
1993-05-18
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544291, A61K 31505, C07D23984
Patent
active
052121763
ABSTRACT:
R(+)-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-6,7-dimethoxy-4-q uinazolinamine hydrochloride or a pharmaceutically acceptable salt or hydratet hereof (terazosin), substantially free of the S(-)-enantiomer.
REFERENCES:
patent: 4026894 (1977-05-01), Winn et al.
patent: 4112097 (1978-09-01), Winn et al.
patent: 4251532 (1981-02-01), Roteman
"Advanced Organic Chemistry" by Jerry March (1985) John Wiley & Sons publishers pp. 82-87.
T. Nagatomo, et al., Chem. Pharm. Bull. 35(4)1629-1632 (1987).
Horrom Bruce W.
Kyncl John J.
Abbott Laboratories
Janssen Jerry F.
Page Thurman K.
Venkat Jyothsna
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