(R,S)-1-(3-Hydroxy-4-methoxybenzoyl)-3-hydroxy-2-pyrrolidinone i

Details (R,S)-1-(3-Hydroxy-4-methoxybenzoyl)-3-hydroxy-2-pyrrolidinone i (R,S)-1-(3-Hydroxy-4-methoxybenzoyl)-3-hydroxy-2-pyrrolidinone i

1982-01-20

1984-06-05

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

548544, 548110, A61K 3140, C07D20712

Patent

active

044528078

ABSTRACT:
1-(3-Hydroxy-4-methoxybenzoyl)-3-hydroxy-2-pyrrolidinone of the formula ##STR1## suitable for the control or prevention of cerebral insufficiency is described. The compound contains an asymmetric carbon atom. Therefore, the two optically active enantiomeric forms as well as the racemate are described. The compound of formula I can be prepared by cleaving the protecting group(s) from a corresponding compound in which at least one of the two hydroxy groups is protected.

REFERENCES:
patent: 4239770 (1980-12-01), Kyburz et al.
Yakhontov et al., Chem. Abstr. vol. 86 (1977), 5393r.

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