Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
C435S155000, C435S252300, C435S320100, C435S440000, C435S069100, C435S071100, C435S004000, C435S026000, C536S023200, C536S023740
This invention provides (R)-2-octanol dehydrogenase that catalyzes oxidation-reduction reaction using NAD+(NADH) as a coenzyme and the genes that encodes them. The enzymes of this invention can be obtained from microorganisms such as the generaPichia, Candida, andOgataea, and so on. It is possible to produce alcohols, in particular, alcohols such as (S)-4-halo-3-hydroxybutyric acid esters and (R)-propoxybenzene derivatives by reducing ketones with this (R)-2-octanol dehydrogenase. Moreover, the (R)-2-octanol dehydrogenase of this invention is excellent in activity and stereoselectivity.
patent: 5126256 (1992-06-01), Ebeling et al.
patent: 5385833 (1995-01-01), Bradshaw et al.
patent: 6218156 (2001-04-01), Yasohara et al.
patent: 2003/0054520 (2003-03-01), Bommanus et al.
patent: 01-277494 (1989-11-01), None
patent: 1281092 (1989-11-01), None
patent: 2000-236883 (2000-05-01), None
patent: WO 01/05996 (2001-01-01), None
ChemExper Catalog. 2-Acetonyloxy-3,4-Difluoronitrobenzene.
Mitamura T. et al., “Structure of Isozyme Genes of Glucose Dehydrogenase fromBacillus megateriumIAM1030”, Journal of Fermentation and Bioengineering, vol. 70(6), pp. 363-369 (1990).
Peters J. et al., “A novel NADH-dependent carbonyl reductase with an extremely broad substrate range fromCandida parpsilosis: Purification and characterization”, Enzyme Microb. Technol., vol. 15(11), pp. 950-958 (1993).
Ueda M. et al., “Long-Chain Alcohol Dehydrogenase ofCandidaYeast”, Methods in Enzymology, vol. 188, pp. 171-175 (1990).
Sudovtsov VE, “The Study of the Activity of Alcohol Dehydrogenase From the Cytoplasm of Some Yeasts”, Prikl Biokhim Mikrobiol, vol. 27(1), pp. 61-67 (1991) (English Summary at p. 67).
Luque T. et al., “Structure of theDrosphila melanogasterglutathione-dependent formaldehyde dehydrogenase/octanol dehydrogenase gene (class III alcohol dehydrogenase)”, Eur. J. Biochem., vol. 225(3), pp. 985-993 (1994).
Murdanoto AP. et al., “Purification and Properties of Methyl Formate Synthase, a Mitochondrial Alcohol Dehydrogenase, Participating in Formaldehyde Oxidation in Methylotropnic Yeasts”, Applied and Environmental Microbiology, vol. 63(5), pp. 1715-1720 (1997).
Patel et al., “Microbial production of methylketones: properties of purified yeast secondary alcohol dehydrogenase” J. of Applie Biochemistry, vol. 3, pp. 218-232, 1981.
Bradshaw et al., “A New Alcohol Dehydrogenase with Unique Stereospecificity fromPseudomonassp.”, Bioorganic Chem., 19:398-417, 1991.
Zelinski et al., “Purification and characterization of a novel carbonyl reductase isolted fromRhodococcus erythropolis”, J. of Biotech., 33:283-292, 1994.
Daicel Chemical Industries Ltd.
Fish & Richardson P.C.
Pak Yong D.
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