Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Reexamination Certificate
2007-04-10
2007-04-10
Achutamurthy, P. (Department: 1652)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
C435S155000, C435S252300, C435S320100, C435S440000, C435S069100, C435S071100, C435S004000, C435S026000, C536S023200, C536S023740
Reexamination Certificate
active
10766421
ABSTRACT:
This invention provides (R)-2-octanol dehydrogenase that catalyzes oxidation-reduction reaction using NAD+(NADH) as a coenzyme and the genes that encodes them. The enzymes of this invention can be obtained from microorganisms such as the generaPichia, Candida, andOgataea, and so on. It is possible to produce alcohols, in particular, alcohols such as (S)-4-halo-3-hydroxybutyric acid esters and (R)-propoxybenzene derivatives by reducing ketones with this (R)-2-octanol dehydrogenase. Moreover, the (R)-2-octanol dehydrogenase of this invention is excellent in activity and stereoselectivity.
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Kudoh Masatake
Yamamoto Hiroaki
Achutamurthy P.
Daicel Chemical Industries Ltd.
Fish & Richardson P.C.
Pak Yong D.
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