Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ortho-hydroxybenzoic acid or derivative doai
Patent
1988-02-04
1989-08-15
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ortho-hydroxybenzoic acid or derivative doai
514305, 546133, A61K 31625, C07D45302
Patent
active
048575178
ABSTRACT:
Certain specific substituted 9-N-(1-azabicyclo-[2.2.2.]octan-3-yl)carboxamido-2,3,4,5-tetrahydro-1-benz oxepins and their valuable use as 5-HT.sub.3 antagonists having CNS and gastric prokinetic acticity and void of any significant D.sub.2 receptor binding properties are disclosed. Methods for their preparation also are described.
REFERENCES:
patent: 3103515 (1963-09-01), Zaugg et al.
Campbell Henry F.
Klein Scott I.
Kuhla Donald E.
Youssefyeh Raymond
Rorer Pharmaceutical Corporation
Schwartz Richard A.
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