Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-01-04
2011-01-04
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S322000, C544S356000, C546S133000, C546S143000, C546S268100, C548S216000
Reexamination Certificate
active
07863291
ABSTRACT:
The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.
REFERENCES:
patent: 5053412 (1991-10-01), Fisher et al.
patent: 2007/0004715 (2007-01-01), Huang et al.
patent: 0 337 547 (1989-10-01), None
patent: 0 452 101 (1991-10-01), None
patent: WO 96/06098 (1996-02-01), None
patent: WO 03/092580 (2003-11-01), None
patent: WO 2005/005435 (2005-01-01), None
patent: WO 2006/065209 (2006-06-01), None
patent: WO 2008/000469 (2008-01-01), None
Swain, C.J. et al., “Novel 5-HT3Antagonists: Indol-3-ylspiro(azabicycloalkane-3,5′(4′H)-oxazoles)”, Journal of Medicinal Chemistry, vol. 35, No. 6, pp. 1019-1031 (1992).
Tatsumi, R. et al., “(R)-3′-(3-Methylbenzo[b]thiophen-5-yl)spiro[1-azabicyclo[2,2,2]octane-3,5′-oxazolidin]-2′-one, a Novel and Potent α7 Nicotinic Acetylcholine Receptor Partial Agonist Displays Cognitive Enhancing Properties”, Journal of Medicinal Chemistry, vol. 49, No. 14, pp. 4374-4383 (2006).
Cook, II James H.
Iwuagwu Christiana I.
King Dalton
Macor John E.
McDonald Ivar M.
Algieri Aldo A.
Bristol--Myers Squibb Company
Epperson James
Willis Douglas M
Wilson James O
LandOfFree
Quinuclidine compounds as alpha-7 nicotinic acetylcholine... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Quinuclidine compounds as alpha-7 nicotinic acetylcholine..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quinuclidine compounds as alpha-7 nicotinic acetylcholine... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2643671