Quinoxalinone derivatives and analytical method using said compo

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

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436131, 436161, 436172, C07D24144, G01N 3352, G01N 3002, G01N 2164

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active

048002232

ABSTRACT:
A quinoxalinone derivative of the following formula: ##STR1## where R.sub.1 and R.sub.2 are each methyl, ethyl or propyl; and R.sub.3 is a chlorine atom or azide, is a reagent capable of high-sensitivity labelling for fluorescence that reacts quantitatively with each of primary, secondary and tertiary hydroxyl groups to provide for easy labelling for fluorescence and which allows quantitative analyzing over a wide detection range.

REFERENCES:
patent: 4264600 (1981-04-01), Abdulla et al.
patent: 4296114 (1981-10-01), Appleton et al.
Goto et al., Chem. Pharm. Bull., 29(3), 899-901 (1981).
Takadate et al., Chem. Pharm. Bull., 33(3), 1164-1169 (1985).
Goto et al., Anal. Chim. Acta, 147, 397-400 (1983).
Wintersteiger et al., J. Chromat., 237, 399-406 (1982).
Yamaguchi et al., J. Chromat., 346, 227-236 (1985).
Sen et al., Chemical Abstracts, vol. 55, 22329a (1961).

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