Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-03-13
2007-03-13
Tucker, Zachary C. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S250000, C544S344000, C544S347000, C544S353000
Reexamination Certificate
active
10826439
ABSTRACT:
The invention provides substituted quinoxalines having the general formulaswhere R1, R2, R3, and R4are, inter alia, alkyl, aryl, or heteroaryl groups; Z is NH or O; and X is, inter alia, COOH or CONH2. The compounds of the invention have antiviral and immunomodulatory activity and are useful for treating infectious diseases, particularly viral infections.
REFERENCES:
patent: 3510487 (1970-05-01), Bolhofer et al.
patent: 3656953 (1972-04-01), Schlunke et al.
patent: 6103720 (2000-08-01), Lubisch et al.
patent: 6482949 (2002-11-01), Sessler et al.
patent: 6518423 (2003-02-01), Kaneko et al.
patent: 2004/0006104 (2004-01-01), Bush et al.
Spicer et al, “Dimeric Analogs of Non-Cationic Tricyclic Aromatic Carboxamides are a New Class of Cytotoxic Agents” Anti-Cancer Drug Design, vol. 14(3), pp. 281-289 (1999).
Hawley's Condensed Chemical Dictionary, 12th ed., Richard J. Lewis, Sr. , © 1993 by Van Nostrand Reinhold. p. 594.
Concise Encyclopedia Chemistry, edited by Drs. Hans-Dieter Jakubke and Hans Jeschkeit, © 1993 by Walter de Gruyter & Co., p. 490.
McGraw-Hill Dictionary of Chemical Terms, 3rd ed. edited by Sybil P. Parker, © 1984 McGraw-Hill, Inc., p. 200.
Silk, J.A. “Quinoxaline N-Oxides. V. Further bz-Substituted Derivatives” Journal of the Chemical Society, pp. 2058-2063 (1956).
Gum and Joullié “Structure vs. Reactivity in Quinoxalinecarboxylic Acids and Esters” Journal of Organic Chemistry, vol. 30(11), pp. 3982-3985 (1965).
Batulina et al, “N-Oxides of N-phenazinoyl Derivatives of Some α-Amino Acids” Khimiko-Farmatsevticheskii Zhurnal, vol. 4(11), pp. 18-22 (1970). As Abstracted by Caplus.
Kora et al, “Synthesis and Antimicrobial Activity of Some New 2,3-dichloroquinoxaline-6-sulfonyl Amino Acid Deriviatives” Polish Journal of Chemistry, vol. 62(7-12), pp. 749-756 (1988) As Abstracted by Caplus.
Sueszer et al, “Preparation and Laboratory Evaluation of Cellulose-Based Ion Permselective Membranes” Desalination, vol. 7(1), pp. 47-50 (1969).
An Haoyun
Chow Suetying
Harris Clayton
Rong Frank
Wu Jim
Brown & Raysman Millstein Felder & Steiner LLP
Demers James P.
Tucker Zachary C.
Valeant Research and Development
LandOfFree
Quinoxaline derivatives having antiviral activity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Quinoxaline derivatives having antiviral activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quinoxaline derivatives having antiviral activity will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3762604