Quinoneimines of malonic acid diamides

Details Quinoneimines of malonic acid diamides Quinoneimines of malonic acid diamides

2004-07-23

2010-02-16

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C514S616000

Reexamination Certificate

active

07663000

ABSTRACT:
The present invention provides optionally substituted compounds of the formula I or salts thereof;wherein R1is O or S when double bonded to the ring or is OH, SH, or a protected equivalent, when single bonded to the ring, R2is hydrogen or more preferably an C1-C10organic group attached by a carbon atom, X is H, O, OO, S or SS R3is absent where X═H, is hydrogen or is a hydroxyl or thiol protecting group, R4is a hetero- or preferably homo-cyclic aryl group, optionally substituted with a further group R5and groups T1are each, independently, absent, hydrogen or an S—R6group, where any/each R6is independently an organic group of molecular weight up to around 500 amu. The invention further provides a method for the synthesis of such compounds and a method of treatment comprising administering such compounds to a mammalian subject.

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