Quinone derivative...

Details Quinone derivative... Quinone derivative...

2011-07-12

2011-07-12

Henley, III, Raymond J (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ketone doai

C514S171000

Reexamination Certificate

active

07977388

ABSTRACT:
Use of idebenone for the preparation of a medicament for the treating of a muscular dystrophy in particular for treating and/or preventing weakness and/or loss of skeletal muscle tissue and/or cardiomyopathy associated with a muscular dystrophy.

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patent: WO 2006/007910 (2006-01-01), None
McNally, Elizabeth, et al, “Cardiomyopathy in Muscular Dystrophy Workshop Sep. 28-30, 2003, Tuscon, Arizona,” Neuromuscular Disorders, vol. 14, pp. 442-448 (2004).
Silversides, Candice, et al, “Effects of Deflazacort on the Left Ventricular Function in Patients With Duchenne Muscular Dystrophy,” The American College of Cardiology, vol. 91, pp. 769-772 (Mar. 2003).
International Search Report for PCT/EP2006/002536 dated Jul. 20, 2006.
Mealy et al., “Annual Update 2004/2005—Treatment of Neurological Disorders,” Drugs of the Future, vol. 30, No. 11, 2005, pp. 1107-1200.
Osako, “The Effects of Idebenone and Glycyrrhizin onmdxMouse Muscle,” Journal of the Medical Society of Toho University, vol. 46, No. 1, 1999, pp. 72-80 (English abstract).
Kurihara et al., “Electrical myotonia and cataract in X-linked muscular dystrophy (mdx) mouse,” Journal of the Neurological Sciences, vol. 99, No. 1, Oct. 1990, pp. 83-92.
English translation of First Office Action (Notice of Reasons for Rejection) received in counterpart Japanese Patent Application No. 2008-502302 dated Feb. 7, 2011 (2 pages).
Ministry of Welfare, the Japanese Government (by trust money on mental
eurological disorder research), article entitled, “Research on the pathology and treatment of muscular dystrophy and related diseases,” Takagi Group, Research Report of 1995, Mar. 1996 (in Japanese, with partial English translation) (8 pages).

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