Quinolylaminobenzoylpiperazine-1-oxides

Details Quinolylaminobenzoylpiperazine-1-oxides Quinolylaminobenzoylpiperazine-1-oxides

1974-09-23

1976-11-16

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424250, C07D29516

Patent

active

039923827

ABSTRACT:
Novel compounds of the formula: ##SPC1##
Are disclosed with the corresponding hydrates and pharmaceutically acceptable acid addition salts thereof, wherein R.sub.1 is halogen, lower alkyl, or trifluoromethyl; R.sub.2 is lower alkyl, substituted or unsubstituted phenyl or benzyl and R.sub.3 is hydrogen. The novel compounds are useful for the treatment of hypertension and anxiety in mammals, including humans.
Disclosed also are compositions containing the novel compounds of the invention and methods of their use in the treatment of hypertension and anxiety.

REFERENCES:
patent: 3047579 (1962-07-01), Witman
patent: 3632761 (1972-01-01), Graham et al.
patent: 3755332 (1973-08-01), Wasley et al.
patent: 3884921 (1975-05-01), Cotrel et al.

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