Quinolones with anti-HIV activity

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S290000

Reexamination Certificate

active

07019141

ABSTRACT:
The present invention relates to inhibition of viruses, e.g., HIV using quinolones and compounds related to quinolones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

REFERENCES:
patent: 3141888 (1964-07-01), Loev
patent: 50069085 (1975-09-01), None
Caplus English Abstract DN 67:120195, PI FR 4390 Oct. 10, 1966, Love Bernard . 1a,7b-Dihydr-1H-cyclopropa[c]quinoline compositions.
Caplus, English Abstract DN 62:2986, 1-Methyl-3,4-dihydroquinolin-2-one . . . Love B et al.
Caplus English Abstract WO 2001077100 , Arnold E et al Synthesis of benzoamide piperidine . . . Oct. 18, 2001.
Reiko Fujita, et al., “Diels-Alder Cycloadditions of 2(1H)-Quinolones Having an Electron-Withdrawing Group at 3-Position Acting as Dienophiles with Dienes,”Chem. Pharm. Bull, 49(7):893-899 (2001).
English Abstract Caplus DN 81:3745, “Migration of Ortho-Substituents in Enamide Photocyclization,”Journal of the Chemical Society, 3:81-82 (1974) RN 53085-91-1P.

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