Quinolonecarboxylic acid derivatives and their use

Details Quinolonecarboxylic acid derivatives and their use Quinolonecarboxylic acid derivatives and their use

1994-03-08

1996-05-21

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514312, 540575, 544324, 544349, 544350, 544363, 546113, 546114, 546156, C07D41704, C07D41706, A61K 31495

Patent

active

055190243

ABSTRACT:
A composition comprises a 1,7-disubstituted-4-oxo-3-quinolinecarboxylic acid or 1,7-disubstituted-4-oxo-3-naphthyridinecarboxylic acid derivative which is useful as a prophylactic and/or therapeutic agent for peripheral arterial obstruction, acute myocardial infarction, an antitumor agent, and as a prophylactic and/or therapeutic agent for osteoporosis.

REFERENCES:
patent: 5039805 (1991-08-01), Alig et al.
patent: 5258510 (1993-11-01), Ogawa et al.
Patent Abstracts of Japan, vol. 11, No. 101, Mar. 31, 1987 (C-413) corresponding to JP-A-61 251 667 (Nov. 6, 1986)
Patent Abstracts of Japan, vol. 14, No. 443, Sep. 21, 1990 (C-0762) corresponding to JP-A-02 174 797 (Jul. 6, 1990).
Domagala et. al., J. Med Chem. 31, pp. 991-1001 (1988).
Izzo et. al., J. Heterocyclic Chem. 25, pp. 289-295 (1988).
Chemical Abstracts, 114:206981 (1990).
Chemical Abstracts, 112:210528 (1989).

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