Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1994-09-16
1995-09-05
Gupta, Yogendra N.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514212, 540544, 540597, A61K 3155, C07D40104, C07D40110, C07D41710
Patent
active
054479266
ABSTRACT:
A quinolone carboxylic acid derivative having the following formula (1), ##STR1## wherein R.sup.1 is a hydrogen atom, an alkyl group, an aralkyl group, an ester residual group which can be hydrolyzed in living bodies, R.sup.2 is a hydrogen atom or an amino group which may be substituted by one or two lower alkyl groups, X is a hydrogen atom or a halogen atom, Y is CH.sub.2, O, S, SO, SO.sub.2, or N--R.sup.3, wherein R.sup.3 is a hydrogen atom or a lower alkyl group, and Z is an oxygen atom or two hydrogen atoms; or a salt thereof; and an antimicrobial agent comprising the same. The compound exhibits a superior antimicrobial activity, especially against gram positive microorganisms, and is thus useful for the treatments and prevention of various infectious diseases in clinics.
REFERENCES:
patent: 5073556 (1991-12-01), Iwata et al.
patent: 5140033 (1992-08-01), Schriewer et al.
patent: 5324735 (1994-06-01), Shibata et al.
Asaoka Takemitsu
Kawahara Ryuichi
Konno Fujiko
Kuraishi Tasdayuki
Matsuda Hideaki
Gupta Yogendra N.
SS Pharmaceutical Co., Ltd.
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