Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-11-14
1990-05-08
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3144
Patent
active
049238787
ABSTRACT:
Compounds of formula I and its pharmaceutically acceptable salts are formulated with a pharmaceutical carrier for the treatment or prevention of neoplastic diesase states sensitive to such treatment in animals including humans ##STR1## wherein: A is an alkyl group having 1-6 carbons;
REFERENCES:
patent: 4788202 (1988-11-01), Ward
Cancer Res. 48, 589-601, 2/1988--Shoemaker, et al., Feasibility of Drug Screening with Panels of Human Tumor Cell Lines Using a Microculture Tetrazolium Assay.
Cancer Res. 48, 4827-4833, 9/1988--Shoemaker, et al., Evaluation of a Soluble Tetrazolium/Formazan Assay for Cell Growth and Drug Sensitivity in Culture Using Human and Other Tumor Cell Lines.
Huff Joel R.
Oliff Allen I.
Caruso Charles M.
Goldberg Jerome D.
Merck & Co. , Inc.
Pfeiffer Hesna J.
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