Quinolinecarboxylic acid derivatives, antibacterial agent contai

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142332, 544105, 544115, C07D41304, A61K 31535

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active

051662035

ABSTRACT:
Novel quinolinecarboxylic acid derivatives of the formula: ##STR1## wherein Z is ##STR2## or ##STR3## in which R.sup.1 is hydrogen atom, a halogen atom, hydroxy or a lower alkyloxy; R.sup.2 is a halogen atom, hydroxy or a lower alkyloxy; R.sup.3 is a lower alkyl; and R.sup.4 is hydroxy or a di(lower alkyl)amino, and a pharmaceutically acceptable salt thereof, which have excellent antibacterial activities and are useful as an antibacterial agent, a pharmaceutical composition containing the same, and process for preparing the same.

REFERENCES:
patent: 4382892 (1983-05-01), Hayakawa et al.
patent: 4808584 (1989-02-01), Taguchi et al.
patent: 4853469 (1989-08-01), Taguchi et al.
patent: 4971967 (1990-11-01), Kondo et al.
Kondo et al, Chemical Abstracts, vol. 114, entry 10205(g) (1991).
Proceedings of the 109th Annual Meetings of the Pharmaceutical Society of Japan, Nagoya 1989, vol. IV, p. 30 with English translation.

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