Quinoline sulfonamides and their therapeutic use

Details Quinoline sulfonamides and their therapeutic use Quinoline sulfonamides and their therapeutic use

1997-05-20

1998-11-10

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514312, 514313, 514314, 546153, 546155, 546156, 546157, 546159, 546160, 546168, 546169, 546170, 546172, C07D21536, A61K 3147

Patent

active

058344853

ABSTRACT:
The subject invention pertains to quinolinesulfonamides. The subject compounds can be used to treat disease states, such as those that are associated with proteins that mediate cellular activity, for example, by inhibiting phosphodiesterase IV (PDE IV) or tumor necrosis factor (TNF). The invention also pertains to methods of treating disease states, including those states capable of being modulated by inhibition of PDE IV or TNF.

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