Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-09-06
1992-09-22
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514314, 544 49, 546172, 546174, 546175, 546176, 546180, A61K 3147, C07D40512, C07D40912, C07D21514
Patent
active
051497034
ABSTRACT:
Compounds having the formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.
REFERENCES:
patent: 4876346 (1989-10-01), Musser et al.
patent: 5015661 (1991-05-01), Armin
patent: 5082849 (1992-01-01), Huang et al.
Dufresne Claude
Lau Cheuk K.
DiPrima Joseph F.
Lopez Gabriel
Merck Frosst Canada Inc.
Rotman Alan L.
Turnipseed James H.
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