Quinoline or quinazoline derivatives, their production and use

Details Quinoline or quinazoline derivatives, their production and use Quinoline or quinazoline derivatives, their production and use

1994-01-26

1995-07-25

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514314, 544284, 546173, A61K 3147, A61K 31505, C07D23974, C07D21560

Patent

active

054362474

ABSTRACT:
A compound represented by the general formula: ##STR1## wherein Y represents a nitrogen atom or C--G (G represents a carboxyl group which may be esterified); ring R is a nitrogen-containing unsaturated heterocyclic group which may be substituted or unsubstituted; each of rings A and B may have a substituent; n represents an integer from 1 to 4; k represents the integer 0 or 1, or a salt thereof, which serves well as an anti-inflammatory agent, particularly a therapeutic agent for arthritis.

REFERENCES:
IL FARMACO, vol. 47, No. 2, Feb. 1992, Italy, pp. 191-202.
Journal of Medicinal Chemistry, vol. 28, No. 10, Oct. 1985, Washington US, pp. 1394-1398.
IL FARMACO, vol. 44, No. 6, Jun. 1989, Italy, pp. 555-563.
Synthesis, No. 9, 1979, Stuttgart DE, pp. 718-719.
European Search Report, EP 9410114.7 1994.
Synthesis, pp. 718-719, Gatta et al., Sep. 1979.
IL FARMACO, 44 (6), pp. 555-563, 1989, M. Anzini et al.

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