Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-03-10
1999-09-14
Huang, Evelyn Mei
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546174, A61K 3147, C07D21536, C07D21514
Patent
active
059523476
ABSTRACT:
Compounds of Formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.
REFERENCES:
patent: 4918081 (1990-04-01), Huang et al.
patent: 4920130 (1990-04-01), Huang et al.
patent: 5104882 (1992-04-01), Young et al.
patent: 5565473 (1996-10-01), Belley
Arison Byron H.
Baillie Thomas A.
Balani Suresh K.
Dufresne Claude
Huang Evelyn Mei
Merck & Co. , Inc.
Rose David L.
Yang Mollie M.
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