Quinoline ether alkanoic acids

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514253, 5142352, 514311, 514314, 544 584, 544128, 544363, 546168, 546169, 546170, 546171, 546172, 546174, 546175, 546176, C07D21514, C07D24104, C07D27912, C07D26530

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active

051028816

ABSTRACT:
Compounds having the formula: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.

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Bundgaapd et al., J. Med. Chem. 1987, 30 451-454.
Saari et al., J. Med. Chem. 1978 21(8), 746-753.

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