Quinoline derivatives, their production and use

Details Quinoline derivatives, their production and use Quinoline derivatives, their production and use

1990-09-25

1993-06-29

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546157, 546163, 514313, A61K 3155, C07D21520

Patent

active

052235130

ABSTRACT:
A quinoline derivative of the formula (I): ##STR1## wherein each phenyl ring of A, B and C can have one or more substituents, X is ##STR2## (R.sup.1 is a hydrogen atom or a lower alkyl group) or ##STR3## (R.sup.2 is a lower alkyl group or a lower alkoxy group), and n is 0 or 1, or its salt, which possesses an inhibitory action against acyl-CoA: cholesterol acyltransferase.

REFERENCES:
patent: 3514459 (1970-05-01), Ritler
patent: 3798226 (1974-03-01), Meguro et al.
patent: 3862152 (1975-01-01), Kuwada et al.
patent: 4530931 (1985-07-01), Musser et al.
patent: 4684645 (1987-08-01), Chang et al.

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