Quinoline derivatives and quinazoline derivatives

Details Quinoline derivatives and quinazoline derivatives Quinoline derivatives and quinazoline derivatives

2007-01-30

2007-01-30

Berch, Mark L. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S287000

Reexamination Certificate

active

10842009

ABSTRACT:
An object of the present invention is to provide compounds which have antitumor activity and do not change cytomorphosis. Disclosed are compounds represented by formula (I) and a pharmaceutically acceptable salts and solvates thereof and pharmaceutical compositions comprising said compounds:wherein X and Z each independently represent CH or N; R1to R3represent H, substituted alkoxy, unsubstituted alkoxy or the like; R4represents H; R5to R8represent H, halogen, alkyl, alkoxy, alkylthio, nitro, or amino, provided that R5to R8do not simultaneously represent H; R9and R10represent H, alkyl, or alkylcarbonyl; and R11represents alkyl, alkenyl, alkynyl, or aralkyl.

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