Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-07-04
2006-07-04
Seaman, D. Margaret (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S291000, C514S310000, C514S312000, C514S320000, C514S321000, C514S322000, C514S323000, C514S191000, C514S252010, C544S333000, C544S392000, C544S071000, C544S165000, C546S153000, C546S155000, C546S192000, C546S193000, C546S195000, C546S197000, C546S198000, C546S199000, C546S200000, C546S201000, C546S202000, C546S205000
Reexamination Certificate
active
07071201
ABSTRACT:
A novel compound of the formula:wherein A, B, C, D, T, Y, and Z represent each methine or nitrogen; R1,R2, R3, R4, and R5represent each a substituent; n represents 0 or an integer of 1 to 3; m represents 0 or an integer of 1 to 6; and p represents an integer of 1 to 3; and pharmacologically acceptable salts thereof. The compound has a serotonin antagonism and is clinically useful as medicament, in particular, for treating, ameliorating and preventing spastic paralysis or central muscle relaxants for ameliorating myotonia.
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Sasakura K. et al. “Simple Synthesis of 1-(azacycloalkyl)indoles using exclusive ortho.alpha.-chloroacetylation of N-(azacycloalkyl)anilines” Synth. Commun.; vol. 18(3); pp. 265-273 (1998).
Kawano Koki
Kimura Teiji
Kitazawa Noritaka
Komatsu Makoto
Kubota Atsuhiko
Birch & Stewart Kolasch & Birch, LLP
Covington Raymond
Eisai Co. Ltd.
Seaman D. Margaret
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