Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-05-17
2005-05-17
Davis, Zinna Northington (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S167000
Reexamination Certificate
active
06894062
ABSTRACT:
The present invention relates to compounds of Formula I,wherein R1, R2, R3, R4, and n are as defined, and to pharmaceutically acceptable salts of said compounds. Compounds of Formula I have activity in agonizing 5HT7 receptors and are useful in treating, for example, disorders that can be treated by modulating circadian rhythms.
REFERENCES:
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Davis, Steven E., 2,4-Diamino-5-benzylpyrimidines and Analogues as Antibacterial Agents. 11.Quinolylmethyl Analogues with Basic Substituents Conveying Specificity, J. Med. Chem, vol. 32, 1989, pp. 1936-1942, XP-002273433.
Jacobs, Christopher, “1-Imidazolyl(alkyl)-Substituted Di-and Tetrahydroquinolines and Analogues Syntheses and Evaluation of Dual Inhibitors of Thromboxane A2 Synthase and Aromatase” J. Med. Chem. vol. 43, 2000, pp. 1841-1851, XP-002273432.
Bright Gene M.
Wlodecki Bishop
Appleman Jolene W.
Davis Zinna Northington
Ling Lorraine B.
Pfizer Inc.
Richardson Peter C.
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