Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2002-06-21
2008-09-16
Seaman, D. Margaret (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S313000, C514S314000, C546S153000
Reexamination Certificate
active
07425564
ABSTRACT:
An objective of the present invention is to provide compounds having potent antitumor activity. The compounds of the present invention are represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof:wherein X=CH or N; Z=O or S; L=O or S; M=CR10R11, wherein R10and R11=H, alkyl, or alkoxy, NR12wherein R12=H or alkyl; R1, R2, and R3=H or optionally substituted alkoxy; R4=H; R5-8=H, halogen, alkoxy or the like; and R9=alkyl optionally substituted by —R14, -T-R15, or —NR16R17wherein T=O, S, or NH; R14=an optionally substituted carbocyclic or heterocyclic ring; and R15-17=alkyl or an optionally substituted carbocyclic or heterocyclic ring, or —NR18R19wherein R18and R19=H, optionally substituted alkyl, or an optionally substituted carbocylic or heterocyclic ring, or optionally substituted carbocyclic or heterocyclic ring.
REFERENCES:
patent: 6069151 (2000-05-01), Dyke et al.
patent: 6143764 (2000-11-01), Kubo et al.
patent: 6797823 (2004-09-01), Kubo et al.
patent: 7105669 (2006-09-01), Mortlock et al.
patent: 7135466 (2006-11-01), Sakai et al.
patent: 7169789 (2007-01-01), Kubo et al.
patent: 7211587 (2007-05-01), Kubo et al.
patent: 860 433 (1998-06-01), None
patent: 860433 (1998-06-01), None
patent: 00/43366 (2000-07-01), None
patent: 01/47890 (2001-07-01), None
patent: 01/48790 (2001-07-01), None
patent: 02/32872 (2002-04-01), None
U.S. appl. No. 10/491,898, filed Apr. 16, 2004, Miwa et al.
U.S. appl. No. 10/480,632, filed Dec. 22, 2003, Fujiwara et al.
U.S. appl. No. 10/132,473, filed Apr. 26, 2002, Kubo et al.
U.S. appl. No. 09/889,858, filed Jul. 23, 2001, Kubo et al.
Fujiwara Yasunari
Miwa Atsushi
Nakamura Kazuhide
Nishitoba Tsuyoshi
Osawa Tatsushi
Kirin Beer Kabushiki Kaisha
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
Seaman D. Margaret
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