Quinoline-containing ketoacids as leukotriene antagonists

Details Quinoline-containing ketoacids as leukotriene antagonists Quinoline-containing ketoacids as leukotriene antagonists

1992-02-07

1993-05-18

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546172, H01N 4342, C07D21536

Patent

active

052121801

ABSTRACT:
Compounds having the formula I: ##STR1## are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection.

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